Understanding the outcome of clinical therapies on cognitive function is an important aspect of the drug discovery process. Objective cognitive testing in early phase clinical trials can provide insight into subtle, but important effects on a participant’s mental functions (including the ability to perceive, process, store information, make decisions and produce appropriate responses).
Cognitive testing can be deployed at pre-screening to ensure you have appropriate participants taking part in your study and to assess investigational medicinal product effects on different cognitive domains such as:
- Memory and recall
- Processing/reaction speed
- Speech and language
- Attention/Executive functions
- Social Cognition
This understanding can benefit the drug discovery process by informing decisions to progress candidate compounds, dose-response relationships, selection of safe doses, detection of off-target effects and risk/benefit to the target indication.
The Science Behind brings both experience of study design and award-winning scientific experience in cognitive psychology research to offer a service that can be integrated with proposed clinical study protocols.
We will work closely with CROs at the study design stage to ensure that appropriate tests and analytic approaches are deployed to provide clinically meaningful results.